Andover — Martin S. Sinacore, Ph.D. Prominent Boston Scientist, 59.
Dr. Martin (Marty) Sinacore died on November 13, 2012 after having been involved in a tragic bicycling accident.
Marty devoted his scientific career to the creation and manufacture of drugs so that others could live and have better lives. He had a long and successful career in biotechnology research, development and manufacturing, including over twenty years at Genetics Institute and Wyeth BioPharma and most recently at Biogen Idec. He was deeply involved and played important leadership roles in both product development and technology, with particular emphasis in the field of mammalian cell culture. His laboratory teams played a central role in the development of production cell lines used for the manufacture of many biopharmaceutical drugs, both investigational and commercial. Marty’s strong scientific background, breadth of expertise and experience, as well as organizational, mentoring and collaboration skills also made him a natural leader of interdisciplinary project teams, and he contributed to the advancement of many products in that capacity. He and his team performed pioneering research on the development of Chinese Hamster Ovary (CHO) cells to grow in serum-free, suspension culture, which helped to pave the way for higher-performing, more economical and safer production of complex recombinant DNA-derived biotech products. Throughout his career he continued to drive the use of new technologies and approaches to make the development and manufacture of biopharmaceuticals more effective from a quality, consistency and cost perspective.
He frequently presented his work at prestigious international scientific and industry conferences and his work was published in top peer-reviewed journals. Marty was also well-recognized and appreciated for his enthusiastic participation in and nurturing of the cell culture community, and provided much service in organizing and supporting national and international scientific conferences. Marty founded the Upstream Process Development Forum of the Massachusetts Biotechnology Council, a group that included scientists from various biotech companies in the Boston area. They meet to exchange knowledge and ideas every other month.